Serenoa Repens, thanks to its extract rich in fatty acids and phytosterols, contributes to maintain the health of the prostate, helping the functionality of the urinary tract and the drainage of liquids. Also, as demonstrated by large scientific evidence, Serenoa Repens thank to its muscle relaxant activity and anti inflammatory properties is actively effective in counteracting and alleviating the symptoms of the prostate swelling.
Natural Supplement For Men Prostate Health Care With Saw Palmetto And Organic Lycopene In Synergy With Selenium
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Products Description
Health Prostate Plus with Serenoa Repens, Lycopene and Selenium is a natural solution for all men over 40 who proactively wish to prevent and/or counteract the disorders caused by BPH (Benign Prostatic Hypertrophy). Made of synergistic ingredients, Health Prostate Plus contributes to the natural wellness of the prostate and to the well being of the urinary tract. A daily intake of Health Prostate Plus helps to:
✅ improve the urinary flux and keep it at normal level;
✅ prevent inflammation and prostatitis helping a better emptying of the bladder;
✅ reduce the frequency of urination, particularly at night;
✅ reduce the urinary urgency;
✅ improve the drainage of liquids;
✅ guarantee an effective antioxidant action, fundamental for the prostate health.
✅ prevent inflammation and prostatitis helping a better emptying of the bladder;
✅ reduce the frequency of urination, particularly at night;
✅ reduce the urinary urgency;
✅ improve the drainage of liquids;
✅ guarantee an effective antioxidant action, fundamental for the prostate health.
Main Active Ingredients & Benefits
The combination of Serenoa Repens Extract, Lycopene and Selenium has a beneficial action much stronger than the sum of the individual ingredients taken separately, resulting helpful in preventing and counteracting the symptoms of the inflamed and swollen prostate. Thanks to the synergy of its components, Health Prostate Plus contributes to the natural well being of the prostate and the urinary tract.
Saw Palmetto
(Serenoa Repens)
Lycopene
Lycopene, together with Serenoa Repens, contributes to the normal functioning of the prostate and, thanks to its effective antioxidant action, plays an important role in the prevention of BPH. Lycopene contained in Health Prostate Plus has a unique qualitative feature which further improves its effectiveness.
Selenium
Selenium is a microelement essential for men, which fosters the spermatogenesis and it too has an important antioxidant effectiveness, useful for the prostate well being.
Bibliografy
Russo A, Capogrosso P, La Croce G, Ventimiglia E, Boeri L, Briganti A, Damiano R, Montorsi F, Salonia A. Serenoa repens, selenium and lycopene to manage lower urinary tract symptoms suggestive for benign prostatic hyperplasia. Expert Opin Drug Saf. 2016 Dec;15(12):1661-1670. doi: 10.1080/14740338.2016.1190830. Epub 2016 Jun 1. PMID: 27232207.
Minutoli L, Altavilla D, Marini H, Rinaldi M, Irrera N, Pizzino G, Bitto A, Arena S, Cimino S, Squadrito F, Russo GI, Morgia G. Inhibitors of apoptosis proteins in experimental benign prostatic hyperplasia: effects of serenoa repens, selenium and lycopene. J Biomed Sci. 2014 Mar 10;21(1):19. doi: 10.1186/1423-0127-21-19. PMID: 24606563; PMCID: PMC3995880.
Morgia G, Vespasiani G, Pareo RM, Voce S, Madonia M, Carini M, Ingrassia A, Terrone C, Gentile M, Carrino M, Giannantoni A,Blefari F, Arnone S, Santelli G, Russo GI; SPRITE investigators. Serenoa repens + selenium + lycopene vs tadalafil 5 mg for the treatment of lower urinary tract symptoms secondary to benign prostatic obstruction: a Phase IV, non-inferiority, open-label, clinical study (SPRITE study). BJU Int. 2018 Aug;122(2):317-325. doi: 10.1111/bju.14209. Epub 2018 Apr 16. PMID: 29569389.
Cannarella R, Calogero AE, Condorelli RA, Giacone F, Mongioi' LM, La Vignera S. Non-hormonal treatment for male infertility: the potential role of Serenoa repens, selenium and lycopene. Eur Rev Med Pharmacol Sci. 2019 Apr;23(7):3112-3120. doi: 10.26355/eurrev_201904_17595. PMID: 31002161.
Tacklind J, Macdonald R, Rutks I, Stanke JU, Wilt TJ. Serenoa repens for benign prostatic hyperplasia. Cochrane Database Syst Rev. 2012 Dec 12;12(12):CD001423. doi: 10.1002/14651858.CD001423.pub3. PMID: 23235581; PMCID: PMC7084061.
Amdii RE, Al' Shukri AS. [Extract of Serenoa repens in the treatment of benign prostatic hyperplasia and lower urinary tract symptoms]. Urologiia. 2018 May;(2):114-120. Russian. PMID: 29901305.
Rossi A, Mari E, Scarno M, Garelli V, Maxia C, Scali E, Iorio A, Carlesimo M. Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study. Int J Immunopathol Pharmacol. 2012 Oct- Dec;25(4):1167-73. doi: 10.1177/039463201202500435. PMID: 23298508.
Wessagowit V, Tangjaturonrusamee C, Kootiratrakarn T, Bunnag T, Pimonrat T, Muangdang N, Pichai P. Treatment of male androgenetic alopecia with topical products containing Serenoa repens extract. Australas J Dermatol. 2016 Aug;57(3):e76-82. doi: 10.1111/ajd.12352. Epub 2015 May 25. PMID: 26010505.
Ye Z, Huang J, Zhou L, Chen S, Wang Z, Ma L, Wang D, Wang G, Wang S, Liang C,Qiu S, Gu X, Liu J, Weng Z, Wu C, Wei Q, Xie L, Wu W, Cheng Y, Hu J, Wang Z, Zeng X. Efficacy and Safety of Serenoa repens Extract Among Patients with Benign Prostatic Hyperplasia in China: A Multicenter, Randomized, Double-blind,Placebo-controlled Trial. Urology. 2019 Jul;129:172-179. doi: 10.1016/j.urology.2019.02.030. Epub 2019 Mar 14. PMID: 30880074.
Company Profile
Italian Research and Development
Licofarma is a high-tech privately held SME based in South Italy, founded in March 2012 by a team of chemical engineers and laboratory formulators to research the benefits of Lycopene on human health and to use it in the formulation of Skincare and Dietary Supplements. In 2015 Licofarma acquired Pierre Srl, previously operating in the extraction of Lycopene and the formulation of skincare products.
Licofarma has since innovated on these units through research, production & marketing. Licofarma’s team has 25+ years of experience in cosmetic formulations and they have created 200+ professional and OTC natural products with Organic Lycopene. The Company offers solutions to every needs, from holistic everyday skincare to professional protocols and specific skin treatments and health supplements through high quality standards such as:
✅ Encapsulated Organic Lycopene and high grade natural ingredients;
✅ High concentration of active ingredients for increased effectiveness;
✅ No chemical solvents, no GMOs, Cruelty Free;
✅ No parabens, no petrolatum, no mineral oils, no paraffin;
✅ No synthetic preservatives, dyes or perfumes, no SLE/SLES or aggressive surfactants;
✅ Tested for Nickel, Chrome, Cobalt and other heavy metals.
✅ High concentration of active ingredients for increased effectiveness;
✅ No chemical solvents, no GMOs, Cruelty Free;
✅ No parabens, no petrolatum, no mineral oils, no paraffin;
✅ No synthetic preservatives, dyes or perfumes, no SLE/SLES or aggressive surfactants;
✅ Tested for Nickel, Chrome, Cobalt and other heavy metals.
Licofarma’s premises extend over 15,000 m2, including a production site of 2,400 m2; offices and laboratories covering 3,800 m2 and a large green area.
Certifications
Quality Management System ISO 9001:2015
Design and production of cosmetic products and food supplements (Sector IAF: 12,03)
Registration Number
ES-0599/2019
Quality Management System according to the ISO 9001:2015 Standard
Design and production of cosmetic products and food supplements (Sector IAF: 12,03)
ER-0599/2019
Regional Authorization for Production and Packaging of Food Supplements
Released
08 October 2018
Authorization Number
CE IT AIP 160 50
CE IT AIP 160 50
Conformity Certificate Of Organic Product Reg. Ec 834/07 And Ec 889/08
Released for:
Dietary Supplement Lycopene, Lycopene Powder and Lycopene Oleoresin
Codice Odc / CB Code: IT BIO 006 PL0557 (PART I)
Conformity Certificate Of Organic Product Reg. Ec 834/07 And Ec 889/08
Released for:
Dietary Supplement Lycopene, Lycopene Powder and Lycopene Oleoresin
Codice Odc / CB Code: IT BIO 006 PL0557 (PART II)
International Patent
Pubblication Number:
WO2008/015490 A1
Food Supplement based on Biological Lycopene and Process to obtain Biological Lycopene
International Pubblication Date: 07 February 2008
Italian Patent
Pubblication Number:
0001354930
Process for Co-extration of Organic Lycopene and Vegetable Oil Using Supercritical CO2
Pubblication Date:
20 February 2009
United States Patent
Pubblication Number:
US 8,263,156 B2
Food Supplement based on Biological Lycopene and Process to obtain Biological Lycopene
Pubblication Date:
11 September 2012 (PART I)
United States Patent
Pubblication Number:
US 8,263,156 B2
Food Supplement based on Biological Lycopene and Process to obtain Biological Lycopene
Pubblication Date:
11 September 2012 (PART II)
India Patent
Pubblication Number:
258731
A Process for the Co-Extraction
of Organic Lycopene from
Tomato Berries
Pubblication Date:
03 February 2014
China Patent
Pubblication Number:
ZL 2006 8 0055683.4
Food Supplement based on Biological Lycopene and Process to obtain Biological Lycopene
Pubblication Date:
21 August 2013
Japan Patent
Pubblication Number:
4852151
Food Supplement based on Biological Lycopene and Process to obtain Biological Lycopene
Pubblication Date:
28 October 2011
Italian Patent
Pubblication Number:
0001371860
Fractionation of Liquid Matrices containing Anthocyanins with Supercritical CO2
Pubblication Date:
22 Mars 2010
Canadian Patent
Pubblication Number:
CA 2 714 718
Food Supplement based on Biological Lycopene and Process to obtain Biological Lycopene
Pubblication Date:
02 July 2008
Italian Patent
Pubblication Number:
0001383967
Face and Body Aesthetic Treatment with Microdermabrasion Technique
Pubblication Date:
23 December 2010
Manufacturing Technique
Licofarma is a high technology Italian firm committed to the research of clean biotechnology extraction methods, in order to extract natural active ingredients without the use of chemical solvents. Together with our research partners, including the University of Salento, CNR Ispa Bari-Lecce and thanks to the Italian Ministry of Research, Licofarma has focused on and patented an innovative extraction process which uses Supercritical CO2 to extract natural antioxidants instead of the traditional toxic-noxious chemical solvents.
Production Technology
Supercritical CO2 extraction is to date the best way to extract natural antioxidants without using chemical solvents. The idea is: at very high pressure, some substances which are in gas form at room temperature can suddenly liquefy and be used for the extraction of natural and vegetable nutrients. When above 31°C of temperature (critical temperature) and 73 bars of pressure (critical pressure), CO2 acquires intermediate features between gas and liquid, and therefore it can be used as solvent to extract low molecular weight and little polar active ingredients from vegetable or animal sources.
Technology Advantages
Compared to chemical solvents, Supercritical CO2 shows significant advantages:
✅It allows higher quality natural products, carrying the same “natural” features of the original sources and without trace of chemical solvents.
✅Extraction cycle is short and simple.
✅ Production plant is eco-friendly and does not pollute the environment. The extraction residuals don’t contain chemical solvents, so they are easy to dispose. CO2 is odourless, doesn’t have a flavour, it isn’t toxic (you breath it everyday) and it’s not flammable.
Technology Applications
Some of the processes that Licofarma has patented thanks to this technology relate to:
✅Extraction of Lycopene from organic tomato berries.
✅ Extraction of Anthocyanins from black grapes and other vegetables
✅ Extraction and concentration of Vitamin E from almonds and other vegetables.
✅Extraction and splitting of the antioxidant and aromatic fractions from several officinal herbs, including rosemary and sage.
Our Services
Licofarma is “Your One-Stop Supplier” for
Food Supplements & Skin Care Treatments
Private Label
We can realize your private label either for Cosmetics or Food Supplements. You can choose from one of our formulations which have been already tested and refined to offer you the very best quality available in the market. If you don't have your own artwork or label for your products, we can realize it for you, based on your requirements. We offer a minimum order of as low as 500 units per reference, in this way you can get started with your private label without a large upfront fee.
Contract Manufacturing
We can realize your Cosmetics or Supplements in Contract Maufacturing, covering all the phases of product lifecycle, from R&D to Fomulations through Production. Whether you are looking to develop a single product or an entire product line, we can fulfill all your needs as per OEM or ODM specifications. Additionally we can assist you in the creation of the primary and secondary packaging as per your design requirements. Low minimum order quantity based upon your specifications.
Distribution of Proprietary Brands
We can supply you with our own brands, covering different health or skin care needs.
All our products are made with high concentration of active ingredients, no chemical solvents, no GMOs, cruelty free, no parabens, no mineral oils, no paraffin, no SLE, no petrolathum, no synthetic preservatives, tested for nickel, chrome, cobalt and other heavy metals. Distribution agreement will be reached with every distributors, based on MOQ, payment terms, marketplace and customer service required.
Why Choose Us
\uD83D\uDC8E Key Point 1
Licofarma is the only Company in the world to
offer the most effective antioxidant found in
nature which is our Certified Organic Lycopene extracted from organic tomatoes, pillar of the long lasting Mediterranean diet.
\uD83D\uDC8E Key Point 2
Extremely high production flexibility: typical MOQ for Private Label and Contract Manufacturing is as low as 500-1000units, scalable to over 200.000 units/year. Total customization of packaging, formulas and compositions.
\uD83D\uDC8E Key Point 3
In-house R&D Laboratory, attending every year nearly 10 ingredients trade shows and seminars (incl. In-Cosmetics London, Paris & Monaco, Making-Cosmetics & Sinerga in Milan).
This ensures Licofarma’s customers consistently
benefit from high quality standards, innovation
and latest knowledge of the latest market trends.
\uD83D\uDC8E Key Point 4
Partnership with High-Tech Research & Academic Institutes from Italy to develop Skincare biotechnologies such as high performing peelings & antiwrinkle tensors (Micronized Corundum Powder in Oil-dispersion, Double-Lift Formula) and natural antioxidants deeply absorbed by the skin (Lycocerasome®).
Shipping & Payment Options
Accepted Delivery Terms INCOTERMS:
EXW (EX-Works), FOB (Free on Board)
Shipping Estimated Lead Time per Quantity:
50 units: ready for delivery
51-500 units: 30-90 days
501-10000 units: 120 days
10001+ units: to be negotiated
Accepted Payment Currency: Euro €, US Dollar $
Accepted Payment Type: Bank Transfer, PayPal
Accepted Payment Type: Bank Transfer, PayPal
Payment Term for Licofarma Owned Products:
100% Advanced Payment
Payment Term for
Private Label or Contract Manufacturing:
50% Payment to Order - 50% Before Shipping
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